Joung, J. Keith: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

Tsai, Shengdar Q, Zheng, Zongli, Nguyen, Nhu T, Liebers, Matthew, Topkar, Ved V, Thapar, Vishal, Wyvekens, Nicolas, Khayter, Cyd, Iafrate, A John, Le, Long P, Aryee, Martin J, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2014

Language:

english

File:

PDF, 16.86 MB

english, 2014

2

TALENs: a widely applicable technology for targeted genome editing

Joung, J. Keith, Sander, Jeffry D.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2012

Language:

english

File:

PDF, 391 KB

english, 2012

3

Efficient genome editing in zebrafish using a CRISPR-Cas system

Hwang, Woong Y, Fu, Yanfang, Reyon, Deepak, Maeder, Morgan L, Tsai, Shengdar Q, Sander, Jeffry D, Peterson, Randall T, Yeh, J-R Joanna, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 899 KB

english, 2013

4

CRISPR-Cas systems for editing, regulating and targeting genomes

Sander, Jeffry D, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

5

High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects

Kleinstiver, Benjamin P., Pattanayak, Vikram, Prew, Michelle S., Tsai, Shengdar Q., Nguyen, Nhu T., Zheng, Zongli, Keith Joung, J.

Journal:

Year:

2016

Language:

english

File:

PDF, 10.13 MB

english, 2016

6

Enhanced proofreading governs CRISPR–Cas9 targeting accuracy

Chen, Janice S., Dagdas, Yavuz S., Kleinstiver, Benjamin P., Welch, Moira M., Sousa, Alexander A., Harrington, Lucas B., Sternberg, Samuel H., Joung, J. Keith, Yildiz, Ahmet, Doudna, Jennifer A.

Journal:

Year:

2017

Language:

english

File:

PDF, 11.45 MB

english, 2017

7

Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo

Zuris, John A, Thompson, David B, Shu, Yilai, Guilinger, John P, Bessen, Jeffrey L, Hu, Johnny H, Maeder, Morgan L, Joung, J Keith, Chen, Zheng-Yi, Liu, David R

Journal:

Nature Biotechnology

Year:

2014

Language:

english

File:

PDF, 3.78 MB

english, 2014

8

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Fu, Yanfang, Foden, Jennifer A, Khayter, Cyd, Maeder, Morgan L, Reyon, Deepak, Joung, J Keith, Sander, Jeffry D

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 834 KB

english, 2013

9

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

Fu, Yanfang, Sander, Jeffry D, Reyon, Deepak, Cascio, Vincent M, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2014

Language:

english

File:

PDF, 781 KB

english, 2014

10

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

Tsai, Shengdar Q, Wyvekens, Nicolas, Khayter, Cyd, Foden, Jennifer A, Thapar, Vishal, Reyon, Deepak, Goodwin, Mathew J, Aryee, Martin J, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2014

Language:

english

File:

PDF, 1.19 MB

english, 2014

11

Defining and improving the genome-wide specificities of CRISPR–Cas9 nucleases

Tsai, Shengdar Q., Joung, J. Keith

Journal:

Nature Reviews Genetics

Year:

2016

Language:

english

File:

PDF, 1.16 MB

english, 2016

12

Prediction of off-target activities for the end-to-end design of CRISPR guide RNAs

Listgarten, Jennifer, Weinstein, Michael, Kleinstiver, Benjamin P., Sousa, Alexander A., Joung, J. Keith, Crawford, Jake, Gao, Kevin, Hoang, Luong, Elibol, Melih, Doench, John G., Fusi, Nicolo

Journal:

Nature Biomedical Engineering

Year:

2018

Language:

english

File:

PDF, 1.98 MB

english, 2018

13

Enhanced Proofreading Governs CRISPR-Cas9 Targeting Accuracy

Chen, Janice S., Dagdas, Yavuz S., Kleinstiver, Benjamin P., Welch, Moira M., Sousa, Alexander A., Harrington, Lucas B., Sternberg, Samuel H., Joung, Keith J., Yildiz, Ahmet, Doudna, Jennifer A.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 44 KB

english, 2018

14

Impact of Genetic Variation on CRISPR-Cas Targeting

Canver, Matthew C., Joung, J. Keith, Pinello, Luca

Journal:

The CRISPR Journal

Year:

2018

Language:

english

File:

PDF, 697 KB

english, 2018

15

An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities

Gehrke, Jason M, Cervantes, Oliver, Clement, M Kendell, Wu, Yuxuan, Zeng, Jing, Bauer, Daniel E, Pinello, Luca, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2018

Language:

english

File:

PDF, 1.36 MB

english, 2018

16

CRISPResso2 provides accurate and rapid genome editing sequence analysis

Clement, Kendell, Rees, Holly, Canver, Matthew C., Gehrke, Jason M., Farouni, Rick, Hsu, Jonathan Y., Cole, Mitchel A., Liu, David R., Joung, J. Keith, Bauer, Daniel E., Pinello, Luca

Journal:

Nature Biotechnology

Year:

2019

Language:

english

File:

PDF, 777 KB

english, 2019

17

CRISPR DNA base editors with reduced RNA off-target and self-editing activities

Grünewald, Julian, Zhou, Ronghao, Iyer, Sowmya, Lareau, Caleb A., Garcia, Sara P., Aryee, Martin J., Joung, J. Keith

Journal:

Nature Biotechnology

Year:

2019

Language:

english

File:

PDF, 2.06 MB

english, 2019

18

Identifying and modifying protein–DNA and protein–protein interactions using a bacterial two-hybrid selection system

Journal:

Journal of Cellular Biochemistry

Year:

2001

Language:

english

File:

PDF, 111 KB

english, 2001

19

Targeted mutagenesis in zebrafish using customized zinc-finger nucleases

Foley, Jonathan E, Maeder, Morgan L, Pearlberg, Joseph, Joung, J Keith, Peterson, Randall T, Yeh, Jing-Ruey J

Journal:

Nature Protocols

Year:

2009

Language:

english

File:

PDF, 765 KB

english, 2009

20

FLASH assembly of TALENs for high-throughput genome editing

Reyon, Deepak, Tsai, Shengdar Q, Khayter, Cyd, Foden, Jennifer A, Sander, Jeffry D, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2012

Language:

english

File:

PDF, 3.89 MB

english, 2012

21

Locus-specific editing of histone modifications at endogenous enhancers

Mendenhall, Eric M, Williamson, Kaylyn E, Reyon, Deepak, Zou, James Y, Ram, Oren, Joung, J Keith, Bernstein, Bradley E

Journal:

Nature Biotechnology

Year:

2013

Language:

english

File:

PDF, 520 KB

english, 2013

22

Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition

Kleinstiver, Benjamin P, Prew, Michelle S, Tsai, Shengdar Q, Nguyen, Nhu T, Topkar, Ved V, Zheng, Zongli, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

23

Open-source guideseq software for analysis of GUIDE-seq data

Tsai, Shengdar Q, Topkar, Ved V, Joung, J Keith, Aryee, Martin J

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 169 KB

english, 2016

24

Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells

Kleinstiver, Benjamin P, Tsai, Shengdar Q, Prew, Michelle S, Nguyen, Nhu T, Welch, Moira M, Lopez, Jose M, McCaw, Zachary R, Aryee, Martin J, Joung, J Keith

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 756 KB

english, 2016

25

731. High-Fidelity CRISPR-Cas9 Nucleases with No Detectable Genome-Wide Off-Target Effects

Kleinstiver, Benjamin P., Pattanayak, Vikram, Prew, Michelle S., Tsai, Shengdar Q., Nguyen, Nhu T., Joung, J. Keith

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 358 KB

english, 2016

26

CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets

Tsai, Shengdar Q, Nguyen, Nhu T, Malagon-Lopez, Jose, Topkar, Ved V, Aryee, Martin J, Joung, J Keith

Journal:

Year:

2017

Language:

english

File:

PDF, 1.05 MB

english, 2017

27

Allele-Specific CRISPR-Cas9 Genome Editing of the Single-Base P23H Mutation for Rhodopsin-Associated Dominant Retinitis Pigmentosa

Li, Pingjuan, Kleinstiver, Benjamin P., Leon, Mihoko Y., Prew, Michelle S., Navarro-Gomez, Daniel, Greenwald, Scott H., Pierce, Eric A., Joung, J. Keith, Liu, Qin

Journal:

The CRISPR Journal

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

28

Defining CRISPR–Cas9 genome-wide nuclease activities with CIRCLE-seq

Lazzarotto, Cicera R., Nguyen, Nhu T., Tang, Xing, Malagon-Lopez, Jose, Guo, Jimmy A., Aryee, Martin J., Joung, J. Keith, Tsai, Shengdar Q.

Journal:

Nature Protocols

Year:

2018

Language:

english

File:

PDF, 1011 KB

english, 2018

29

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

Grünewald, Julian, Zhou, Ronghao, Garcia, Sara P., Iyer, Sowmya, Lareau, Caleb A., Aryee, Martin J., Joung, J. Keith

Journal:

Year:

2019

Language:

english

File:

PDF, 25.62 MB

english, 2019

30

Adopt a moratorium on heritable genome editing

Lander, Eric S., Baylis, Françoise, Zhang, Feng, Charpentier, Emmanuelle, Berg, Paul, Bourgain, Catherine, Friedrich, Bärbel, Joung, J. Keith, Li, Jinsong, Liu, David, Naldini, Luigi, Nie, Jing-Bao, Q

Journal:

Year:

2019

Language:

english

File:

PDF, 1.54 MB

english, 2019

31

Adopt a moratorium on heritable genome editing

Lander, Eric S., Baylis, Françoise, Zhang, Feng, Charpentier, Emmanuelle, Berg, Paul, Bourgain, Catherine, Friedrich, Bärbel, Joung, J. Keith, Li, Jinsong, Liu, David, Naldini, Luigi, Nie, Jing-Bao, Q

Journal:

Year:

2019

File:

PDF, 1.54 MB

2019

32

Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function

Cruz, Lilian, GyÃ¶rgy, Bence, Cheah, Pike See, Kleinstiver, Benjamin P., Eimer, William A., Garcia, Sara P., Sharma, Nutan, Ozelius, Laurie J., Bragg, D. Cristopher, Joung, J. Keith, Norberto de Souza

Journal:

Molecular Therapy — Nucleic Acids

Year:

2020

File:

PDF, 33.37 MB

2020

33

CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells

Kurt, Ibrahim C., Zhou, Ronghao, Iyer, Sowmya, Garcia, Sara P., Miller, Bret R., Langner, Lukas M., GrÃ¼newald, Julian, Joung, J. Keith

Journal:

Nature Biotechnology

Year:

2020

File:

PDF, 17.73 MB

2020

34

ZFNGenome: A comprehensive resource for locating zinc finger nuclease target sites in model organisms

Deepak Reyon, Jessica R Kirkpatrick, Jeffry D Sander, Feng Zhang, Daniel F Voytas, J Keith Joung, Drena Dobbs, Clark R Coffman

Journal:

Year:

2011

Language:

english

File:

PDF, 1.03 MB

english, 2011

35

Activation of prokaryotic transcription through arbitrary protein–protein contacts

Dove, Simon L., Joung, J. Keith, Hochschild, Ann

Journal:

Year:

1997

File:

PDF, 926 KB

1997

36

High-frequency modification of plant genes using engineered zinc-finger nucleases

Townsend, Jeffrey A., Wright, David A., Winfrey, Ronnie J., Fu, Fengli, Maeder, Morgan L., Joung, J. Keith, Voytas, Daniel F.

Journal:

Year:

2009

Language:

english

File:

PDF, 210 KB

english, 2009

37

Reply to “Genome editing with modularly assembled zinc-finger nucleases”

Joung, J Keith, Voytas, Daniel F, Cathomen, Toni

Journal:

Year:

2010

Language:

english

File:

PDF, 116 KB

english, 2010

38

Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays

Maeder, Morgan L, Thibodeau-Beganny, Stacey, Sander, Jeffry D, Voytas, Daniel F, Joung, J Keith

Journal:

Nature Protocols

Year:

2009

Language:

english

File:

PDF, 1.02 MB

english, 2009

39

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection

Pattanayak, Vikram, Ramirez, Cherie L, Joung, J Keith, Liu, David R

Journal:

Year:

2011

Language:

english

File:

PDF, 865 KB

english, 2011

40

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

Sander, Jeffry D, Cade, Lindsay, Khayter, Cyd, Reyon, Deepak, Peterson, Randall T, Joung, J Keith, Yeh, Jing-Ruey J

Journal:

Nature Biotechnology

Year:

2011

Language:

english

File:

PDF, 174 KB

english, 2011

41

A Synthetic Biology Framework for Programming Eukaryotic Transcription Functions

Khalil, Ahmad S., Lu, Timothy K., Bashor, Caleb J., Ramirez, Cherie L., Pyenson, Nora C., Joung, J. Keith, Collins, James J.

Journal:

Year:

2012

Language:

english

File:

PDF, 627 KB

english, 2012

42

Electroanatomic Remodeling of the Left Stellate Ganglion After Myocardial Infarction

Seongwook Han, Kenzaburo Kobayashi, Boyoung Joung, Gianfranco Piccirillo, Mitsunori Maruyama, Harry V. Vinters, Keith March, Shien-Fong Lin, Changyu Shen, Michael C. Fishbein, Peng-Sheng Chen, Lan S.

Journal:

Journal of the American College of Cardiology

Year:

2012

Language:

english

File:

PDF, 1.89 MB

english, 2012

43

Robust, synergistic regulation of human gene expression using TALE activators

Maeder, Morgan L, Linder, Samantha J, Reyon, Deepak, Angstman, James F, Fu, Yanfang, Sander, Jeffry D, Joung, J Keith

Journal:

Year:

2013

Language:

english

File:

PDF, 325 KB

english, 2013

44

CRISPR RNA–guided activation of endogenous human genes

Maeder, Morgan L, Linder, Samantha J, Cascio, Vincent M, Fu, Yanfang, Ho, Quan H, Joung, J Keith

Journal:

Year:

2013

Language:

english

File:

PDF, 649 KB

english, 2013

45

Zinc-finger Nucleases: The Next Generation Emerges

Cathomen, Toni, Keith Joung, J

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 424 KB

english, 2008

46

Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity

Guilinger, John P, Pattanayak, Vikram, Reyon, Deepak, Tsai, Shengdar Q, Sander, Jeffry D, Joung, J Keith, Liu, David R

Journal:

Year:

2014

Language:

english

File:

PDF, 843 KB

english, 2014

47

Comparison of Zinc Finger Nucleases for Use in Gene Targeting in Mammalian Cells

Pruett-Miller, Shondra M, Connelly, Jon P, Maeder, Morgan L, Joung, J Keith, Porteus, Matthew H

Journal:

Molecular Therapy

Year:

2008

Language:

english

File:

PDF, 336 KB

english, 2008

48

What’s Changed with Genome Editing?

Tsai, Shengdar Q., Joung, J. Keith

Journal:

Year:

2014

Language:

english

File:

PDF, 180 KB

english, 2014

49

Allosteric Inhibition of Zinc-Finger Binding in the Major Groove of DNA by Minor-Groove Binding Ligands †

Nguyen-Hackley, Doan H., Ramm, Elizabeth, Taylor, Christina M., Joung, J. Keith, Dervan, Peter B., Pabo, Carl O.

Journal:

Year:

2004

Language:

english

File:

PDF, 578 KB

english, 2004

50

Genome Editing: A Tool For Research and Therapy: Towards a functional understanding of variants for molecular diagnostics using genome editing

Tsai, Shengdar Q, Iafrate, A John, Joung, J Keith

Journal:

Nature Medicine

Year:

2014

Language:

english

File:

PDF, 246 KB

english, 2014